The Cochrane US Network includes 14 Affiliate institutions:
- AcademyHealth
- American College of Physicians
- Central Michigan University
- Cornell University
- Mayo Clinic Evidence-based Practice Center
- Penn Medicine Center for Evidence-based Practice
- RTI International – University of North Carolina Evidence-based Practice Center
- Texas Christian University
- The Ohio State University
- The University of Texas MD Anderson Cancer Center
- University of Chicago Medicine
- University of Colorado Anschutz Medical Campus
- University of Maryland School of Medicine
- U.S. GRADE Network